RECHERCHE Course – BIOACTIVES MOLECULES SPACE ANALYSIS OF MACROMOLECULES (4 ECTS)
(Person in charge: A. Badel)

 

Understanding macromolecules (2 ECTS)
(Persons in charge: D. Flatters)


Program :
Construction of 3D protein models by homology modeling
- 3D structures of biological macromolecules and visualization with Pymol.
Alignment of sequences. Comparison of structures.
- Homology and folding conservation
- Bioinformatics methods for predicting the secondary and tertiary structure of macromolecules
- Construction of 3D protein models by homology modeling

Targeted skills :
3D structures of biological macromolecules and visualization with Pymol. Master the methods of protein and RNA structure prediction and comparative modeling to establish structural models of macromolecules, and evaluate the relevance of a 3D model.